A recent study published in BMC Public Health explores the link between endometriosis and an increased risk of cardiovascular diseases (CVDs), including hypertension and coronary heart disease. This study underscores the importance of recognizing endometriosis as a
cardiovascular risk factor, urging proactive monitoring and intervention for affected women.
What is Endometriosis?
Endometriosis occurs when endometrium-like tissue grows outside the uterus, affecting pelvic organs such as the ovaries, fallopian tubes, bladder, and intestines. These tissues thicken, break down, and bleed with each menstrual cycle, leading to inflammation, pelvic pain, heavy menstrual bleeding, and pain during intercourse. It affects approximately 176 million women worldwide, with 47% of women experiencing infertility also diagnosed with the condition.
Endometriosis and Cardiovascular Disease
- Linked to chronic inflammation, oxidative stress, and high lipid levels, which contribute to atherosclerosis.
- Increased risk of hypertension, hypercholesterolemia, ischemic heart disease (IHD), and myocardial infarction (MI) by 14%, 25%, 40%, and 52%, respectively.
- Despite these risks, the exact biological mechanisms remain unclear, leading to challenges in managing CVD risk in endometriosis patients.
Study Findings on CVD Risk
- A systematic review and meta-analysis examined six cohort studies (2000-2023).
- Women with endometriosis have a 23% increased risk of CVDs and a 13% higher risk of hypertension.
- The study highlights the need for further research to confirm these findings and identify underlying mechanisms.
Possible Biological and Lifestyle Factors
- High estrogen levels may negatively impact the cardiovascular system, causing arterial stiffness and atherosclerotic plaque formation.
- Chronic inflammation and oxidative stress further contribute to heart disease risk.
- Lifestyle factors such as sedentary behavior, poor diet, alcohol consumption, and smoking are common contributors to both conditions.
- Genetic predisposition may also play a role, with European studies identifying genetic loci linked to endometriosis and CVD.
Conclusion & Implications
The first meta-analysis confirming the link between endometriosis and CVD underscores the need for early cardiovascular risk assessment and intervention. Clinicians should integrate anti-inflammatory, oxidative stress-reducing, and hormone-targeting strategies into treatment. Lifestyle changes like a balanced diet, exercise, and stress management, along with personalized care, can help reduce CVD risks in women with endometriosis, ensuring better long-term health.
WellAura’s Commitment to Women’s Heart and Reproductive Health
At WellAura, we believe women’s health goes beyond reproductive wellness—it encompasses heart health, mental well-being, and overall vitality. With growing evidence linking endometriosis to cardiovascular diseases, it is crucial for women to take proactive steps in safeguarding their long-term health.
By recognizing endometriosis as a potential risk factor for cardiovascular disease, WellAura stands by women at every stage of their health journey, ensuring early intervention, personalized care, and long-term wellness.
Follow us on Instagram, Facebook, and LinkedIn for expert tips, health news, and guidance tailored to support your well-being. Reach out today to learn more about our services and how we can help you prioritize your health!
